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Thermostable T7 RNA Polymerase
Engineered heat-resistant DNA-dependent 5'→3' RNA polymerase. Retains stable activity after 42-50°C incubation for 1 hour. Improved transcription efficiency for high-GC RNA, enhanced long dsRNA synthesis, reduced byproducts.
Key Features
- High purity and quality for research applications
- Optimized performance and reliability
- Comprehensive technical support available
Specifications
Product Overview
Thermostable T7 RNA Polymerase is an engineered, heat-resistant, DNA-dependent 5'→3' RNA polymerase expressed in Escherichia coli, which specifically recognizes the T7 promoter sequence. Compared with conventional T7 RNA Polymerase, it exhibits excellent thermostability and retains stable transcriptional activity after incubation at 42–50 °C for 1 hour.
Key Advantages
- Improved transcription efficiency for high-GC RNA
- Enhanced synthesis of long dsRNA
- Reduced formation of dsRNA byproducts
- Decreased immunogenicity of synthesized RNA
Product Components
| Cat. No. | Product Name | Volume |
|---|---|---|
| M008-A | Thermostable T7 RNA Polymerase | 50 U/µL, 25 KU |
| M008-B | 10 × Transcription Buffer | 1 mL×5 |
Storage Conditions
Store at −30 to −15 °C. Ship at ≤0 °C.
Applications
Synthesis of mRNA, siRNA, dsRNA, gRNA; RNA probe synthesis
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